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pentobarbital decreases consequences of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Coadministration of CYP3A4 inducers may possibly lower sufentanil degrees and efficacy, maybe precipitating withdrawal syndrome in patients which have designed Bodily dependence to sufentanil. Discon
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